Our Services
Comprehensive, personalized care for every stage of life, right here in Cape Girardeau, Missouri.
Comprehensive Care for Every Need
From preventive visits to ongoing care for chronic conditions, our services are built around listening first and treating the whole person.

Family Primary Care
Primary care for the whole family, from newborns through seniors. Wellness visits, sick visits, ongoing care for chronic conditions, and the screenings that catch problems early.
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Dementia & Aging Adult Care
Careful, unhurried care for older adults and the families who support them: memory concerns, medication review, coordination with specialists, and caregiver support.
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Wellness & Prevention
Annual wellness visits, cancer screenings, nutrition counseling, and activity guidance, so you can stay ahead of health problems instead of reacting to them.
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Women's Wellness
Women’s health care at every stage, including annual exams, preventive screenings, contraception, and hormone-related concerns, in a space where you can speak freely.
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School, Sports & Employment Physicals
Physicals and screenings for school enrollment, sports participation, and employment requirements, handled thoroughly and scheduled around your calendar.
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Guardian Direct Care
Prefer direct care? Guardian Direct Care is a membership option with transparent pricing and direct access to your provider, offered alongside our insurance-based care.
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Two Ways to Get Care
Guardian Primary Care is in-network with most major commercial insurances, Medicare and Medicaid, so most patients can simply use the coverage they already have.
Prefer direct care? Guardian Direct Care is our membership alternative: accessible, high quality, and transparent, with predictable pricing and no surprise bills. Plans start as low as $40 per month, and fair per-visit pricing is available on request.
How It Works
Getting started with Guardian Primary Care is simple.
Schedule Your Visit
Call us at (573) 200-6143 or request your first appointment online. Visits are by appointment, and you can choose an in-person visit or a telehealth visit, whichever fits your week better.
Meet Your Provider
Preston Holifield, DNP, APRN, FNP-C and our care team take the time to understand your health history, your current concerns, and your goals. You are an active partner in every decision about your care.
Continue Your Care
Care does not end when you leave the office. We follow up, coordinate referrals when you need a specialist, and stay reachable so you know what comes next.
Ready to Begin?
Take the first step toward care that puts you first. Appointments are available in person at our Cape Girardeau office or by telehealth.
