Contact Guardian Primary Care
We would love to hear from you. Call, email or send us a note, and our team will help you take the next step.
Send Us a Message
Use this form for general questions about the practice, Guardian Direct Care or insurance. If you need an appointment soon, calling us at (573) 200-6143 is the fastest way to reach our team.
Visit Us
Guardian Primary Care2441 Myra Dr
Cape Girardeau, MO 63703Get directions on Google Maps →
We serve Cape Girardeau and the surrounding Southeast Missouri communities, including Jackson, Scott City, Perryville and Sikeston.
Office Hours
By Appointment
Closed on US major holidays. Call us and we will find a time that fits your schedule, in the office or by telehealth.
Already a Patient?
Current patients can self-schedule appointments and review their records on the Patient Ally portal. If you need help signing in, call the office and our team will walk you through it.
Find Us in Cape Girardeau
Our clinic is at 2441 Myra Dr in Cape Girardeau, Missouri. Visits are scheduled by appointment, so give us a call and we will get you on the calendar.
New to Guardian? Our new patient page walks through what to bring and what your first visit looks like. Questions about coverage or cost are answered on our Care Access page.