See What Our Patients are Saying...

Patient Testimonials

"I have nothing but positive things to say about Preston and GPC! From working with him on shared patients to trusting him with the care of my family members, he is thorough and very competent.  I love that he takes his time with each patient and looks for real solutions instead of pushing medicine.  I highly recommend him!
- Laura M. Sanders
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"Guardian Primary Care is a fantastic addition to Cape Girardeau! The staff is professional, friendly, and truly cares about their patients. The clinic has a welcoming atmosphere, and the option for both in-person and tele-health appointments makes scheduling so convenient. It’s refreshing to see a healthcare provider that puts such an emphasis on patient comfort and accessibility. Highly recommend for anyone looking for reliable and compassionate primary care!"
- Sho R.
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"Preston is very thorough with his patients. He answers any and all questions that one may have. Highly recommend to anyone looking for a PCP that is easy to get in with and doesn’t break the bank!"
- Mercedes Stiltner
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"I felt very respected and valued here as a patient."
- Brea Baker
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"I’m incredibly grateful for the care of Preston Holifield! He goes above and beyond as a patient advocate, always putting his people first. He serves with kindness and excellence, ensuring every patient receives the best care possible. Despite my tight schedule, he found a way to fit me in, addressed all my needs, and even followed up to make sure everything was going as it should. I highly recommend him—he’s the Chick-fil-A of primary care!"
- Jessica S.
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"Love the practice. Extremely friendly and professional. Really takes the time to listen to their patients and very easy to work with when finding new solutions."
- Jared Mungle
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"Guardian has been a pleasant experience. Preston is very personable and professional. He actually listens and cares about your needs and doesn't feel like he trying to push you through like some places"
- Jeremy Franklin
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- Guardian Primary Care Team

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Office Hours

Monday: 8am-5pm
Tuesday: 8am-5pm
Wednesday: 8am-5pm
Thursday: 8am-5pm
Friday: 8am-5pm

Saturday: Closed
Sunday: Closed

*By Appointment ONLY*
*Holidays May Affect These Hours*
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